Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion
BG Stanley, DR Daniel, AS Chin, SF Leibowitz - Peptides, 1985 - Elsevier
Neuropeptide Y (NPY) injected into the paraventricular nucleus (PVN) is known to elicit a
powerful feeding response in satiated, brain-cannulated rats [41, 42, 43]. The present
experiment investigates the effect of peptide YY (PYY), a structurally-related peptide, on
feeding behavior and, in addition, the effects of both PYY and NPY on the pattern of
macronutrient selection. Injection of PYY directly into the PVN, in doses ranging from 7.8 to
235 pmol/0.3 μl, caused a strong, dose-dependent stimulation of feeding behavior, as well …
powerful feeding response in satiated, brain-cannulated rats [41, 42, 43]. The present
experiment investigates the effect of peptide YY (PYY), a structurally-related peptide, on
feeding behavior and, in addition, the effects of both PYY and NPY on the pattern of
macronutrient selection. Injection of PYY directly into the PVN, in doses ranging from 7.8 to
235 pmol/0.3 μl, caused a strong, dose-dependent stimulation of feeding behavior, as well …