[HTML][HTML] The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity
J Basbous, C Arpin, G Gaudray, M Piechaczyk… - Journal of Biological …, 2003 - ASBMB
The human T-cell leukemia virus type I (HTLV-I)-encoded Tax protein activates transcription
from the viral promoter via association with the cellular basic leucine zipper factor cAMP-
response element-binding protein-2. Tax is also able to induce cellular transformation of T
lymphocytes probably by modulating transcriptional activity of cellular factors, including
nuclear factor-κB, E2F, activator protein-1 (AP-1), and p53. Recently, we characterized in
HTLV-I-infected cells the presence of a novel viral protein, HBZ, encoded by the …
from the viral promoter via association with the cellular basic leucine zipper factor cAMP-
response element-binding protein-2. Tax is also able to induce cellular transformation of T
lymphocytes probably by modulating transcriptional activity of cellular factors, including
nuclear factor-κB, E2F, activator protein-1 (AP-1), and p53. Recently, we characterized in
HTLV-I-infected cells the presence of a novel viral protein, HBZ, encoded by the …