Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments

DB Rein, JS Wittenborn, X Zhang… - Archives of …, 2009 - jamanetwork.com
Objective To forecast age-related macular degeneration (AMD) and its consequences in the
United States through the year 2050 with different treatment scenarios. Methods We
simulated cases of early AMD, choroidal neovascularization (CNV), geographic atrophy
(GA), and AMD-attributable visual impairment and blindness with 5 universal treatment
scenarios:(1) no treatment;(2) focal laser and photodynamic therapy (PDT) for CNV;(3)
vitamin prophylaxis at early-AMD incidence with focal laser/PDT for CNV;(4) no vitamin …