[HTML][HTML] SARS-associated coronavirus quasispecies in individual patients
D Xu, Z Zhang, FS Wang - New England Journal of Medicine, 2004 - Mass Medical Soc
D Xu, Z Zhang, FS Wang
New England Journal of Medicine, 2004•Mass Medical SocTo the Editor: Quasispecies are known in RNA viruses such as hepatitis C virus and human
immunodeficiency virus. 1 Owing to poor fidelity of RNA polymerases, RNA-virus
populations typically contain genetic variants that form a heterogeneous virus pool. The
severe acute respiratory syndrome (SARS)–associated coronavirus, as a newly identified
RNA virus, 2 however, has been reported with relatively limited variations, 3, 4 and no
published data have recorded the existence of quasispecies. During the SARS outbreak …
immunodeficiency virus. 1 Owing to poor fidelity of RNA polymerases, RNA-virus
populations typically contain genetic variants that form a heterogeneous virus pool. The
severe acute respiratory syndrome (SARS)–associated coronavirus, as a newly identified
RNA virus, 2 however, has been reported with relatively limited variations, 3, 4 and no
published data have recorded the existence of quasispecies. During the SARS outbreak …
To the Editor: Quasispecies are known in RNA viruses such as hepatitis C virus and human immunodeficiency virus.1 Owing to poor fidelity of RNA polymerases, RNA-virus populations typically contain genetic variants that form a heterogeneous virus pool. The severe acute respiratory syndrome (SARS)–associated coronavirus, as a newly identified RNA virus,2 however, has been reported with relatively limited variations,3,4 and no published data have recorded the existence of quasispecies.
During the SARS outbreak from March to June in 2003, 132 patients with SARS were treated in our unit, including those with the first cluster of cases in the Beijing, China, . . .
The New England Journal Of Medicine