PAGE-B predicts the risk of developing hepatocellular carcinoma in Caucasians with chronic hepatitis B on 5-year antiviral therapy

G Papatheodoridis, G Dalekos, V Sypsa… - Journal of …, 2016 - Elsevier
Background & Aims Risk scores for hepatocellular carcinoma (HCC) developed in Asians
offer poor-moderate predictability in Caucasian patients with chronic hepatitis B (CHB). This
nine center cohort study aimed to develop and validate an accurate HCC risk score in
Caucasian CHB patients treated with the current oral antivirals, entecavir/tenofovir. Methods
We included 1815 adult Caucasians with CHB and no HCC at baseline who received
entecavir/tenofovir for⩾ 12 months. Using data from eight centers (derivation dataset, n …