Analysis of hepatitis B virus transcripts in infected human livers

TS Su, WY Lui, LH Lin, SH Han, FK P'eng - Hepatology, 1989 - journals.lww.com
The hepatitis B virus transcripts in human hepatoma and its adjacent nontumorous liver
were examined with probes specific to hepatitis B virus surface antigen, core antigen, X
region and pre-S region. The study shows that the patterns of hepatitis B virus transcripts for
tumorous tissue and the counterpart in nontumorous liver differ. In most of the tissues
examined, the surface antigen gene is transcribed. Most of these transcripts, besides having
surface antigen sequences, also have an X region; some also include a pre-S region. The …