Long non-coding RNAs in brain development, synaptic biology, and Alzheimer's disease

C Shi, L Zhang, C Qin - Brain research bulletin, 2017 - Elsevier
Long non-coding RNAs (lncRNAs), which are long transcripts without apparent protein-
coding roles, interfere with gene expression and signaling events at various stages.
Increasing evidence has suggested that lncRNAs function in the regulation of tissue
homeostasis and under pathophysiologic conditions. In the nervous system, the expression
of lncRNAs has been detected and characterized under normal physiologic conditions and
in disease states. Some lncRNAs regulate brain development and synaptic plasticity. In …