Direct effects of progesterone and antiprogesterone on human sperm hyperactivated motility and acrosome reaction
ML Uhler, A Leungt, SYW Chan, C Wang - Fertility and sterility, 1992 - Elsevier
Objective To study the direct effects of progesterone (P) and its antagonist RU486
(mifepristone) on sperm hyperactivation (HA) and acrosome reaction. Design Prospective
evaluation of semen samples incubated in capacitation media with P and/or RU486. Setting
University-affiliated tertiary care center. Patients Normal healthy volunteers. Interventions
Semen samples were incubated in media with P or RU486 alone or in combination, and
aliquots were taken at 10 minutes, 1, 5, and 24 hours for HA analyses by computer-aided …
(mifepristone) on sperm hyperactivation (HA) and acrosome reaction. Design Prospective
evaluation of semen samples incubated in capacitation media with P and/or RU486. Setting
University-affiliated tertiary care center. Patients Normal healthy volunteers. Interventions
Semen samples were incubated in media with P or RU486 alone or in combination, and
aliquots were taken at 10 minutes, 1, 5, and 24 hours for HA analyses by computer-aided …