Maternal obesity and gestational diabetes: Impact on arterial wall layer thickness and stiffness in early childhood-RADIEL study six-year follow-up
Background and aims Gestational diabetes (GDM) and maternal obesity are linked to weight
gain in childhood and an increased risk of cardiovascular disease later in life. We assessed
the effects of GDM and maternal obesity on arterial function and morphology in relation to
body anthropometrics and composition in early childhood. Methods We assessed body size
and composition, blood pressure (BP), arterial morphology and stiffness in 201 pairs of
obese mothers (pre-pregnancy BMI 30.7±5.6 kg/m 2, 96 with GDM) and their children at 6.1 …
gain in childhood and an increased risk of cardiovascular disease later in life. We assessed
the effects of GDM and maternal obesity on arterial function and morphology in relation to
body anthropometrics and composition in early childhood. Methods We assessed body size
and composition, blood pressure (BP), arterial morphology and stiffness in 201 pairs of
obese mothers (pre-pregnancy BMI 30.7±5.6 kg/m 2, 96 with GDM) and their children at 6.1 …