Accurate identification of lymph nodes in the mouse is critical for studies of tumor metastasis,
and of regional immune responses following immunization. However, these small lymphatic
organs are often difficult to identify in mice using standard dissection techniques, so that
larger rats have been used to characterize rodent lymphatic drainage. We developed
techniques injecting dye into the mouse footpad or tail, to label the lymphatic drainage of the
hind leg and flank, pelvic viscera, prostate and mammary glands. While lymphatic drainage …